Shotgun Presentations

BL

Ben Lee, PhD Student

Affiliation: University of Exeter Medical School (UK)
Title: Splicing Regulatory Factors and Lifespan in Mouse Models
LL

Ling Li, PhD Student

Affiliation: University of Exeter Medical School (UK)
Title: Modulation of alternative splicing regulators during EMT in tumour progression
LM

Lisa Müller, PhD Student

Affiliation: Heinrich-Heine-Universität Düsseldorf (Germany)
Title: HEXplorer based analysis of splicing regulatory elements
GH

Gerald Hysenaj, PhD Student

Affiliation: Newcastle University (UK)
Title: System wide identification and analysis of critical Tra2b-controlled exons within the breast cancer transcriptome
ME

Mazdak Ehteramyan, PhD Student

Affiliation: King’s College London, London (UK)
Title: Identification of a novel shear stress responsive gene in the intron of Laf4
OR

Om Rathore, PhD Student

Affiliation: University of Algarve, Algarve (Portugal)
Title: Available Soon.
MB

Maxime Blijlevens, PhD Student

Affiliation: VUmc Cancer Center Amsterdam, Amsterdam (Netherlands)
Title: High-throughput functional screening identifies cancer-selective lethal targets in the RNA spliceosome
AM

Ainhoa Martinez, PhD Student

Affiliation: Universidad Autonoma de Madrid, Madrid (Spain)
Title: Functional analysis and therapeutic approaches for two splicing mutations identified in aPTPS-deficient patient
AM

Adam Mol, PhD Student

Affiliation: Technical University of Darmstadt (Germany)
Title: Control of protein translocation by synthetic riboswitches in human cells
TA

Tessa Arends, PhD Student

Affiliation: University of Colorado Denver- Anschutz Medical Campus, National Jewish Health (USA)
Title: Control of signaling and response in B cells through regulation of alternative RNA splicing
ZB

Zoe Blackley, PhD Student

Affiliation: University of Nottingham (UK)
Title: SRPK1 Inhibition as a Novel Analgesic Strategy
MB

Maxime Blijlevens, PhD Student

Affiliation: VUmc Cancer Center Amsterdam, Amsterdam (Netherlands)
Title: Available Soon.
JW

Juste Wesche, PhD Student

Affiliation: Institute of Molecular Toxicology & Pharmacology, Helmholtz Zentrum Munich (Germany)
Title: The Jumonji domain-containing protein 6 (Jmjd6) – an important splicing regulator?
WD

Wojtek Drabarek, PhD Student

Affiliation: Erasmus University Medical Center (Netherlands)
Title: The effect of spliceosome inhibitor E7107 on SF3B1 mut uveal melanoma cell lines
NL

Nina Lackner, PhD Student

Affiliation: University Hospital of the Paracelsus Medical University Salzburg, Salzburg (Austria)
Title: Antisense RNA-mediated improvement of SMaRT therapy for KRT14 correction
NA

Nuno Saraiva-Agostinho, PhD Student

Affiliation: Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon (Portugal)
Title: psichomics: a bioinformatics application for the quantification, analysis and visualisation of alternative splicing from large transcriptomic datasets
MB

Marie Bordone, PhD Student

Affiliation: Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon (Portugal)
Title: The alternative splicing landscape of neurodegenerative disorders: decoupling disease-specific effects from loss of neurons
MB

Mariana Ascenção-Ferreira, PhD Student

Affiliation: Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon (Portugal)
Title: Profiling the alternative splicing landscape of senescent cells
SJ

Samantha Jumbe, PhD Student

Affiliation: Faculty of Health and Applied Science, University of the West of England (UK)
Title: Function of the Cassette Exon 7b of the Transcription Factor ERG
UA

Usama Ashraf, PhD Student

Affiliation: Institut Pasteur (France)
Title: Structural analysis of the human RED-SMU1 splicing complex and potential for host-directed anti-influenza therapy
NA

Najate AIT-ALI, PhD Student

Affiliation: INSERM (France)
Title: The Regulation of alternative splicing of the nucleoredoxin-like 1 gene
SU

Simon Uzor, PhD Student

Affiliation: University of the West of England (UK)
Title: Treatment of prostate cancer cells with the CLK1 inhibitor TG003 reduces tumour cell growth and induces apoptosis
DR

Denise Rawcliffe, PhD Student

Affiliation: Umeå University (Sweden)
Title: Regulation of the incorrect splicing of ISCU in HML
RS

Rosina Savisaar, PhD Student

Affiliation: The Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath (UK)
Title: Functional exonic splice enhancers are common and under strong selection
NK

Napsugár Kavalecz, PhD Student

Affiliation: University of Debrecen (Hungary)
Title: A lariat branch point motif-interrupted spliceosomal twin intron in Aspergillus nidulans
CD

Cristina Domingos, PhD Student

Affiliation: Kingston University London (UK)
Title: Splice variants of matricellular proteins in cancer
PZ

Peter Zorn, PhD Student

Affiliation: Martin-Luther-University Halle-Wittenberg (Germany)
Title: Rbfox1 mediates splicing control in cardiovascular disease
AL

Ángeles Arzalluz-Luque, PhD Student

Affiliation: Centro de Investigación Príncipe Felipe (Spain)
Title: Single-cell RNAseq for the study of isoforms: how is that possible?
LF

Lorena de la Fuente, PhD Student

Affiliation: Centro de Investigación Príncipe Felipe (Spain)
Title: Regulation of 3’untranslated regions along neural differentiation systems
FP

Francisco Pardo, PhD Student

Affiliation: Centro de Investigación Príncipe Felipe (Spain)
Title: Differential Splicing across tissues of maize B73 cultivar and their functional implications
AF

Alexandra Filatova, PhD Student

Affiliation: Research Centre of Medical Genetics (Russia)
Title: Congenital aniridia is caused by PAX6 mutations affecting splicing
VV

Vindhya Vijay, PhD Student

Affiliation: College of Medicine, University of Florida (USA)
Title: The Role of Aberrant mRNA Splicing in Cancer
NM

Naseeb Malhi, PhD Student

Affiliation: University of Nottingham (UK)
Title: The SRPK1 inhibitor SPHINX31 stabilises retinal permeability in vitro and in vivo models of diabetes
GQ

Gaë Quéré, PhD Student

Affiliation: Inserm U1078-ECLA, Faculté de Médecine (France)
Title: Available Soon.
AB

Antoine Bernard, PhD Student

Affiliation: Département de Biologie et de Pathologie des Tumeurs, INSERM (France)
Title: Available Soon.
HE

Hatice Esenkaya, PhD Student

Affiliation: University of Leicester, University Road (UK)
Title: Investigating the effects of G-quadruplex stabilising ligands on alternative splicing of Bcl-x and Mcl-1 pre-mRNA in vivo
JS

Juliana Inês Pinto dos Santos, PhD Student

Affiliation: Instituto Nacional de Saúde Doutor Ricardo Jorge (Portugal)
Title: Development of an U1 snRNA-adapted gene therapeutic strategy to correct a 5′ splicing defect causing a lysosomal storage disease
MM

Mercedes del Río Moreno, PhD Student

Affiliation: Maimonides Institute for Biomedical Research of Córdoba (IMIBIC) University of Córdoba, Córdoba (Spain)
Title: Hepatic Steatosis in Obese Women is Associated with a Dysregulation in Splicing Machinery
EP

Emilia M Alors Pérez, PhD Student

Affiliation: Maimonides Institute for Biomedical Research of Córdoba (IMIBIC) University of Córdoba, Córdoba (Spain)
Title: Peptides derived from the extracellular domain of the oncogenic sst5TMD4 splicing variant of the somatostatin receptor 5 increase malignancy of cancer cells
JV

Juan Manuel Jiménez Vacas, PhD Student

Affiliation: Maimonides Institute for Biomedical Research of Córdoba (IMIBIC) University of Córdoba, Córdoba (Spain)
Title: Antitumoral effects of the splicing inhibitor Pladienolide-B in prostate cancer cells
SA

Sergio Pedraza-Arévalo, PhD Student

Affiliation: Maimonides Institute for Biomedical Research of Córdoba (IMIBIC) University of Córdoba, Córdoba (Spain)
Title: Splicing machinery is deeply dysregulated and associated with malignancy in pancreatic neuroendocrine tumors